33 Results for "

Swietenia humilis Zucc.

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "Swietenia humilis Zucc." in MCE Product Catalog:

6
Toosendanin
Toosendanin
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6 Publications Verification
Cat. No.: HY-N0263
CAS No.: 58812-37-6
Category:  

Triterpenes Terpenoids Melia toosendan Sieb. et Zucc. Plants Disease Research Fields Inflammation/Immunology Meliaceae

Target:  

Others

Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .
6
Cornuside
Cornuside
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6 Publications Verification
Cat. No.: HY-N0631
CAS No.: 131189-57-6
Category:  

Cornaceae Iridoids Cornus officinalis Sieb. et Zucc. Terpenoids Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

p38 MAPK NF-κB JNK Cholinesterase (ChE) Acyltransferase NO Synthase Interleukin Related TNF Receptor Prostaglandin Receptor ERK COX

Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation .
1
β,β-Dimethylacrylshikonin
β,β-Dimethylacrylshikonin
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1 Cited Publications
Cat. No.: HY-N5112B
CAS No.: 24502-79-2
Synonyms: Isoarnebin I
Category:  

Quinones Phenols Polyphenols Plants Lithospermum erythrorhizon Sieb. et Zucc. Disease Research Fields Boraginaceae Naphthalene Quinones Cancer

Target:  

HIF/HIF Prolyl-Hydroxylase Apoptosis Notch NO Synthase Bcl-2 Family

β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative that can be isolated from Lithospermum erythrorhizon Sieb. et Zucc. β,β-Dimethylacrylshikonin promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. β,β-Dimethylacrylshikonin inhibits Notch-1 activation. β,β-Dimethylacrylshikonin inhibtis tumor cell proliferation, induces tumor cell apoptosis, and inhibits tumor growth .
1
Emodin-1-O-β-D-glucopyranoside
Emodin-1-O-β-D-glucopyranoside
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1 Cited Publications
Cat. No.: HY-N2394
CAS No.: 38840-23-2
Category:  

Quinones Rheum palmatum L. Polygonaceae Anthraquinones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Bacterial

Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC50 of 0.85 μM .
(E/Z)-Polydatin
(E/Z)-Polydatin
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Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
Category:  

Stilbenes Polygonaceae Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Drug Isomer

(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products and chocolate products. Polydatin exhibits multiple biological properties, such as anti-platelet aggregation, anti-low-density lipoprotein oxidation, cardioprotective activity, anti-inflammatory and immunomodulatory functions. Polydatin shows favorable cytotoxic effects against various tumor cell lines, including cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells .
10-Deacetyltaxol
10-Deacetyltaxol
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Cat. No.: HY-N1391
CAS No.: 78432-77-6
Synonyms: 10-Deacetylpaclitaxel
Category:  

Terpenoids Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus wallichiana Zucc.

Target:  

Microtubule/Tubulin

10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .
Vitisin A
Vitisin A
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Cat. No.: HY-142026
CAS No.: 142449-89-6
Synonyms: (+)-Vitisin A
Category:  

Vitis vinifera cv. Zalema Phenols Polyphenols Plants Vitaceae

Target:  

Caspase ERK NF-κB Influenza Virus PAK LDLR PPAR PCSK9 Androgen Receptor Keap1-Nrf2 Monoamine Oxidase Cholinesterase (ChE) IKK Wnt β-catenin Reactive Oxygen Species (ROS) Apoptosis Cuproptosis

Vitisin A ((+)-Vitisin A) is an orally active natural product with multiple pharmacological activities including anti-inflammatory, anti-tumor, anti-oxidant, anti-pathogenic microorganism, hypoglycemic and lipid-regulating, anti-osteoporotic, neuroprotective and cardiovascular protective effects. Vitisin A exhibits inhibitory effects on human AChE and MAO-B with IC50 values of 1.29 µM and 4.94 µM, respectively. Vitisin A inhibits the ERK, MAPK, NF-κB, STAT1, HMGCR and TRAF6 pathways, downregulates the related phosphorylation and protein expression, while activates the Nrf2/HO-1 pathway and upregulates p21 expression. Vitisin A induces tumor cell apoptosis and cell cycle arrest, inhibits adipogenesis and lipid accumulation, while alleviates oxidative stress, suppresses inflammatory responses, blocks hepatic fibrosis, Cuproptosis and cholesterol synthesis, and increases the expression levels of central BDNF and TrkB. Vitisin A can be used in the research of tumors, infectious diseases, metabolic diseases, bone and joint diseases, liver diseases, skin injuries, as well as neurodegenerative and cognitive dysfunction-related diseases .
Guaiacin
Guaiacin
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Cat. No.: HY-N2247
CAS No.: 36531-08-5
Category:  

Zingiber officinale Roscoe Lignans Metabolic Disease Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Zingiberaceae

Target:  

Phosphatase

Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .
β-Sitosterol acetate, 95%
β-Sitosterol acetate, 95%
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Cat. No.: HY-W127616A
CAS No.: 915-05-9
Synonyms: Sitosteryl acetate, 95%
β-Sitosterol acetate, 95% (Sitosteryl acetate, 95%) is a sterol that can be isolated from Hechtia glomerata Zucc., which has antibacterial activity and has a MIC value of 100µg/mL against carbapenem-resistant Acinetobacter baumannii .
1-O-Deacetyl-2α-hydroxykhayanolide E
1-O-Deacetyl-2α-hydroxykhayanolide E
0 Images
Cat. No.: HY-N1640
CAS No.: 1189801-51-1
Category:  

Natural Products Other Diseases Plants Swietenia mahagoni (L.) Jacq. Disease Research Fields Meliaceae

Target:  

Others

1-O-Deacetyl-2α-hydroxykhayanolide E is a natural product that can be isolated from Swietenia mahagoni. 1-O-Deacetyl-2α-hydroxykhayanolide E is widely distributed in the leaves and branches of Swietenia mahagoni .
Swietemahalactone
Swietemahalactone
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Cat. No.: HY-N7322
CAS No.: 1514669-21-6
Category:  

Natural Products Plants Swietenia mahagoni (L.) Jacq. Meliaceae

Target:  

Bacterial

Swietemahalactone is a natural compound isolated from Swietenia mahagoni. Swietemahalactone exhibits antibacterial activity aganist E. coli .
Pachysamine M
Pachysamine M
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Cat. No.: HY-N8956
CAS No.: 1253202-75-3
Category:  

Alkaloids Buxaceae Other Alkaloids Pachysandra terminalis Siebold & Zucc. Plants

Target:  

Others

Pachysamine M (Compound 5) is a pregnane alkaloid. Pachysamine M is isolated from naturalPachysandra terminalisSieb. et Zucc .
Carasinol B
Carasinol B
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Cat. No.: HY-N8929
CAS No.: 777857-86-0
Category:  

Carex humilis Leyss. Cyperaceae Phenols Plants

Target:  

Others

Carasinol B is a Phenols product that can be isolated from the herbs of Carex humilis Leyss .
2-Deacetoxydecinnamoyltaxinine J
2-Deacetoxydecinnamoyltaxinine J
0 Images
Cat. No.: HY-N7756
CAS No.: 87193-98-4
Category:  

Natural Products Taxaceae Plants Taxus wallichiana Zucc.

Target:  

Others

2-Deacetoxydecinnamoyltaxinine J is an active compound that can be isolated from Taxus cuspidta Sibe et Zucc .
7-(2'-Deoxyadenosin-N6-yl)aristolactam I
7-(2'-Deoxyadenosin-N6-yl)aristolactam I
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Cat. No.: HY-N8292
CAS No.: 127191-86-0
Category:  

Alkaloids Aristolochia debilis Siebold & Zucc. Other Alkaloids Plants Aristolochiaceae

Target:  

Others

7-(2'-Deoxyadenosin-N6-yl)aristolactam I is a Alkaloids product that can be isolated from the herbs of Aristolochia debilis Sieb. et Zucc .
Toosendanin (Standard)
Toosendanin (Standard)
0 Images
Cat. No.: HY-N0263R
CAS No.: 58812-37-6
Category:  

Triterpenes Terpenoids Melia toosendan Sieb. et Zucc. Plants Meliaceae

Target:  

Reference Standards Others

Toosendanin (Standard) is the analytical standard of Toosendanin. This product is intended for research and analytical applications. Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .
Ferulic acid sodium (Standard)
Ferulic acid sodium (Standard)
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Cat. No.: HY-N0060AR
CAS No.: 24276-84-4
Synonyms: Coniferic acid sodium (Standard)
Category:  

other families Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Plants Endogenous metabolite

Target:  

Reference Standards FGFR Endogenous Metabolite Reactive Oxygen Species (ROS)

10-Deacetyltaxol (Standard) is the analytical standard of 10-Deacetyltaxol. This product is intended for research and analytical applications. 10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .
10-Deacetyltaxol (Standard)
10-Deacetyltaxol (Standard)
0 Images
Cat. No.: HY-N1391R
CAS No.: 78432-77-6
Synonyms: 10-Deacetylpaclitaxel (Standard)
Category:  

Terpenoids Taxaceae Diterpenoids Plants Taxus wallichiana Zucc.

Target:  

Reference Standards Microtubule/Tubulin

10-Deacetyltaxol (Standard) is the analytical standard of 10-Deacetyltaxol. This product is intended for research and analytical applications. 10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .
Humilinolide A
Humilinolide A
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Cat. No.: HY-N20642
CAS No.: 152110-04-8
Category:  

Tetracyclic Triterpenoids Terpenoids Swietenia humilis Zucc. Plants Meliaceae

Target:  

Herbicide Estrogen Receptor/ERR

Humilinolide A is a limonoid compound. Humilinolide A can be isolated from Swietenia humilis. Humilinolide A binds to estrogen-dependent receptors on the plasma membrane of the myometrium, thereby triggering uterine contraction responses. Humilinolide A induces irreversible, concentration-dependent increases in the tension, amplitude and frequency of smooth muscle contraction. Humilinolide A inhibits radicle growth of barnyard grass (Echinochloa crus-galli) with a IC50 of 99.0 µg/mL. Humilinolide A exhibits antifeedant activity. Humilinolide A can be used in studies related to gastrointestinal motility regulation and reproductive smooth muscle function .
12-O-Methylvolkensin
12-O-Methylvolkensin
0 Images
Cat. No.: HY-N18150
CAS No.: 244179-69-9
Category:  

 Melia azedarach Linn. Natural Products Plants Meliaceae

Target:  

Others

12-O-Methylvolkensin is a limonoid found in the fruits of Melia toosendan Sieb. et Zucc. 12-O-Methylvolkensin shows cytotoxicity against cancer cells. 12-O-Methylvolkensin can be used for the research of cancer, such as human oral epidermoid carcinoma .
Assay Types